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Renal Dose Adjustment

Renal Dose Adjustment: calculated with the published clinical method, with result interpretation. A reference tool that does not replace a doctor's advice.

ℹ Reference calculation based on the published method. It does not replace a clinical examination or a doctor's decision.

Renal Dose Adjustment

Ageyears
Weightkg
Male sex (1 = yes)
Serum creatinineµmol/L
Fraction of drug excreted unchanged in urine (fe)%
Usual dosemg
Adjusted dose
566.7mg
CrCl by Cockcroft–Gault, Dettli factorVerify the dose against the drug labelRenal Dose Adjustment: calculated with the published clinical method, with result interpretation. A reference tool that does not replace a doctor's advice.
Creatinine clearance
51.9mL/min
Kidney function
Moderately decreased (30–59)
Q factor
0.567

More about: Renal Dose Adjustment

What it calculates

The “Renal Dose Adjustment” calculator computes Adjusted dose in mg from 6 parameters: age (years), weight (kg), male sex (1 = yes), serum creatinine (µmol/L), fraction of drug excreted unchanged in urine (fe) (%), usual dose (mg).

Used by professionals and patients to assess health metrics, dosages, and risks.

Example calculation

With parameters Age = 60 years, Weight = 70 kg, Male sex (1 = yes) = 1, Serum creatinine = 132.6 µmol/L, Fraction of drug excreted unchanged in urine (fe) = 90 %, Usual dose = 1,000 mg the result is 566.7 mg (CrCl by Cockcroft–Gault, Dettli factor).

How to use

  1. Enter age, weight, male sex (1 = yes), serum creatinine, fraction of drug excreted unchanged in urine (fe) and usual dose — each field above is adjustable with a slider.
  2. Adjusted dose (mg) is calculated automatically as you type.
  3. Check the worked example below to see the formula applied to real numbers.
  4. Copy the result or bookmark this calculator.

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FAQ

How is BMI calculated?
BMI = weight (kg) / height (m)². Example: 70 kg / (1.75 m)² = 22.9. The WHO normal range is 18.5–24.9; below that is underweight, 25–29.9 is overweight, and 30+ is obese.
Is BMI accurate for everyone?
No. BMI does not distinguish muscle from fat, so athletes may show a high BMI with low body fat. It is also less reliable for teenagers, pregnant people, older adults, and very tall or short individuals.
What are the BMI categories?
Underweight: below 18.5. Normal: 18.5–24.9. Overweight: 25–29.9. Obese class I: 30–34.9; class II: 35–39.9; class III: 40+.
What is a better measure than BMI?
Body fat percentage, waist-to-height ratio (aim for under 0.5), and waist circumference give a clearer picture of health than BMI alone.

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