DOAC Renal Dosing

DOAC Renal Dosing: calculated with the published clinical method, with result interpretation. A reference tool that does not replace a doctor's advice.

ℹ Reference calculation based on the published method. It does not replace a clinical examination or a doctor's decision.

DOAC Renal Dosing

Drug (1 apixaban, 2 rivaroxaban, 3 dabigatran, 4 edoxaban)
Ageyears
Body weightkg
Male sex (1 = yes)
Creatinineµmol/L
Verapamil (1 = yes)
Ciclosporin, dronedarone, erythromycin or ketoconazole (1 = yes)
Single dose
5mg
Atrial fibrillation; doses per EU labels and EHRA 2021Verify the dose against the product labelDOAC Renal Dosing: calculated with the published clinical method, with result interpretation. A reference tool that does not replace a doctor's advice.
Creatinine clearance (Cockcroft–Gault)
59.9mL/min
Dosing frequency
Twice daily
Recommendation
Standard dose

More about: DOAC Renal Dosing

What it calculates

The “DOAC Renal Dosing” calculator computes Single dose in mg from 7 parameters: drug (1 apixaban, 2 rivaroxaban, 3 dabigatran, 4 edoxaban), age (years), body weight (kg), male sex (1 = yes), creatinine (µmol/L), verapamil (1 = yes), ciclosporin, dronedarone, erythromycin or ketoconazole (1 = yes).

Used by professionals and patients to assess health metrics, dosages, and risks.

Example calculation

With parameters Drug (1 apixaban, 2 rivaroxaban, 3 dabigatran, 4 edoxaban) = 1, Age = 75 years, Body weight = 75 kg, Male sex (1 = yes) = 1, Creatinine = 100 µmol/L, Verapamil (1 = yes) = 0, Ciclosporin, dronedarone, erythromycin or ketoconazole (1 = yes) = 0 the result is 5 mg (Atrial fibrillation; doses per EU labels and EHRA 2021).

How to use

  1. Enter drug (1 apixaban, 2 rivaroxaban, 3 dabigatran, 4 edoxaban), age, body weight, male sex (1 = yes), creatinine, verapamil (1 = yes) and ciclosporin, dronedarone, erythromycin or ketoconazole (1 = yes) — each field above is adjustable with a slider.
  2. Single dose (mg) is calculated automatically as you type.
  3. Check the worked example below to see the formula applied to real numbers.
  4. Copy the result or bookmark this calculator.

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FAQ

How is BMI calculated?
BMI = weight (kg) / height (m)². Example: 70 kg / (1.75 m)² = 22.9. The WHO normal range is 18.5–24.9; below that is underweight, 25–29.9 is overweight, and 30+ is obese.
Is BMI accurate for everyone?
No. BMI does not distinguish muscle from fat, so athletes may show a high BMI with low body fat. It is also less reliable for teenagers, pregnant people, older adults, and very tall or short individuals.
What are the BMI categories?
Underweight: below 18.5. Normal: 18.5–24.9. Overweight: 25–29.9. Obese class I: 30–34.9; class II: 35–39.9; class III: 40+.
What is a better measure than BMI?
Body fat percentage, waist-to-height ratio (aim for under 0.5), and waist circumference give a clearer picture of health than BMI alone.

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