Hepatic Dose Adjustment
Hepatic Dose Adjustment: calculated with the published clinical method, with result interpretation. A reference tool that does not replace a doctor's advice.
ℹ Reference calculation based on the published method. It does not replace a clinical examination or a doctor's decision.
Hepatic Dose Adjustment
Total bilirubinµmol/L
Albuming/L
INR
Ascites: 1 none, 2 mild, 3 moderate/severe
Encephalopathy: 1 none, 2 grade 1–2, 3 grade 3–4
Child-Pugh score
8points
Child-Pugh class
B
Dose adjustment
Moderate impairment: dose reduction often needed
More about: Hepatic Dose Adjustment
What it calculates
The “Hepatic Dose Adjustment” calculator computes Child-Pugh score in points from 5 parameters: total bilirubin (µmol/L), albumin (g/L), inr, ascites: 1 none, 2 mild, 3 moderate/severe, encephalopathy: 1 none, 2 grade 1–2, 3 grade 3–4.
Used by professionals and patients to assess health metrics, dosages, and risks.
Example calculation
With parameters Total bilirubin = 40 µmol/L, Albumin = 30 g/L, INR = 1.5, Ascites: 1 none, 2 mild, 3 moderate/severe = 2, Encephalopathy: 1 none, 2 grade 1–2, 3 grade 3–4 = 1 the result is 8 points (Check the dose against the drug label).
How to use
- Enter total bilirubin, albumin, inr, ascites: 1 none, 2 mild, 3 moderate/severe and encephalopathy: 1 none, 2 grade 1–2, 3 grade 3–4 — each field above is adjustable with a slider.
- Child-Pugh score (points) is calculated automatically as you type.
- Check the worked example below to see the formula applied to real numbers.
- Copy the result or bookmark this calculator.
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FAQ
How is BMI calculated?
BMI = weight (kg) / height (m)². Example: 70 kg / (1.75 m)² = 22.9. The WHO normal range is 18.5–24.9; below that is underweight, 25–29.9 is overweight, and 30+ is obese.
Is BMI accurate for everyone?
No. BMI does not distinguish muscle from fat, so athletes may show a high BMI with low body fat. It is also less reliable for teenagers, pregnant people, older adults, and very tall or short individuals.
What are the BMI categories?
Underweight: below 18.5. Normal: 18.5–24.9. Overweight: 25–29.9. Obese class I: 30–34.9; class II: 35–39.9; class III: 40+.
What is a better measure than BMI?
Body fat percentage, waist-to-height ratio (aim for under 0.5), and waist circumference give a clearer picture of health than BMI alone.
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